Microarray Suggestion Criteria

The National Institute of Allergy and Infectious Diseases (NIAID) supported Pathogen Functional Genomics Resource Center (PFGRC) designs, constructs, and distributes glass slide DNA microarrays for pathogens and biodefense related organisms (Select A-C agents). Currently, the PFGRC supports DNA microarrays for the 38 organisms listed here. In continuing its efforts to provide the infectious disease and biodefense communities with the microarray resources most relevant to their research efforts, the PFGRC is soliciting input for selection of its next set of reference/species microarrays. The criteria for organism selection may be found here.

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White Papers

The National Institute of Allergy and Infectious Diseases (NIAID)/NIH/DHHS Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute (JCVI) supports "White Papers" in the areas of Gene Expression studies, Comparative Genomics, Gene Knock Outs, Proteomics and Bioinformatics as well as associated methodologies and technologies. It is our desire to continue to identify the most relevant resources and collaborative opportunities between the scientific community and our Center. The PFGRC makes its resources, technology platforms, and scientific and technical expertise available for functional genomics and proteomics studies for the purpose of developing genomic/proteomic data sets of broad interest and value to the scientific community. To this end, the "White Paper" concept is designed to provide outreach to the scientific community such that investigators can propose collaborative projects that are responsive to the greater resource and research needs of the infectious disease and biodefense communities utilizing the extensive resources and expertise provided by the PFGRC.

The PFGRC conducted its first White Paper solicitation during the summer of 2007. The projects listed in the table below were chosen for support and collaboration. As results and datasets become available, appropriate links will be provided in the Resources and Reagents column.

Project Description

Reagents and Resources

Collaborators

Vibrio Vulnificus microarray

V. vulnificus microarray

Paul Gulig, University of Florida

Campylobacter jejuni microarray

C. jejuni microarray

Patricia Guerry, Naval Medical Research Center

Vibrio parahemolyticus microarray

V. parahemolyticus microarray

Crystal Johnson, University of Southern Mississippi Gulf Coastal Research Laboratory

Helicobacter pylori Gateway Clone Set

H. pylori Gateway Clone Set

Scott Merrell, Uniformed Services University

Comparative genomic study of Clostridium botulinum

Data Set
future release

Eric Johnson, University of Wisconsin-Madison

Isolation and characterization of environmental Bacillus isolates harboring B. anthracis virulence genes

Data Set
future release

Alex Hoffmaster, Centers for Disease Control

Label-free protein arrays

Data Set
future release

Milan Mrksich, University of Chicago

Proteomic comparisons in closely related or congenicsusceptible and drug-resistant mutants

Data Set
future release

David Alland, University of Medicine and Dentistry of New Jersey

Genetic tools for studying functional genomics and infection biology of M. tuberculosis

M. tuberculosis bar code array
future release

Gyanu Lamichhane, The Johns Hopkins University School of Medicine