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The NIAID sponsored Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute is pleased to announce the release of three new, free open-source software tools: Magnolia, Ginkgo and APEX. Magnolia is a microarray data management and export system for researchers who use PFGRC microarrays. The software greatly simplifies the tasks of organizing experimental data and submitting it to a public data repository. Ginkgo is a Comparative Genomic Hybridization (CGH) and expression microarray data analysis package. Several normalization, data filtering and imputation, and replicate microarray functions are implemented in an intuitive graphical framework. The APEX tool is an implementation of the Absolute Protein Expression quantitation technique. It can compute protein abundance values for LC-MS/MS proteomics datasets, quantifying hundreds or thousands of proteins. Links to additional information on each of these new software tools is available from the PFGRC's bioinformatics page.

The National Institute of Allergy and Infectious Diseases (NIAID) supported Pathogen Functional Genomics Resource Center (PFGRC) designs, constructs, and distributes glass slide DNA microarrays for pathogens and biodefense related organisms (Select A-C agents). Currently, the PFGRC supports DNA microarrays for the 38 organisms listed here. In continuing its efforts to provide the infectious disease and biodefense communities with the microarray resources most relevant to their research efforts, the PFGRC is soliciting input for selection of its next set of reference/species microarrays. The criteria for organism selection may be found here.

Scientific Advisory Committee

Name	Title	Institute
Roger Brent	Director and President	The Molecular Sciences Institute
Gail H. Cassell	Vice President, Infectious Diseases	Drug Discovery Research and Clinical Investigation Eli Lilly and Company
Joe DeRisi	Assistant Professor Biochemistry & Biophysics	University of California at San Francisco
Michael B. Eisen		Lawrence Berkeley National Labs, and Department of Molecular and Cellular Biology University of California at Berkeley
Stanley Falkow	Professor Microbiology and Immunology	Stanford University School of Medicine
David Gelfand		Roche Molecular Systems, Inc
Hamilton Smith		J. Craig Venter Institute
Mitchell L. Sogin	Director, Josephine Bay Paul Center	Marine Biological Laboratory
Thomas Whittam	Hannah Distinguished Professor	National Food Safety & Toxicology Center Michigan State University