June 3, 2010
Katsura - Metabolic Pathway Coverage and Expression Analysis Tool
The NIAID sponsored Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute has developed a software tool that overlays gene expression or comparative genomic hybridization data onto KEGG metabolic pathways. The Katsura tool utilizes data from the Kyoto Encyclopedia of Genes and Genomes (KEGG) to construct a local database. Katsura gives researchers capabilities to manage and update the KEGG pathway and enzyme data related to a collection of user selected genomes. Gene expression data or CGH data is imported into the tool to allow visualization of gene expression related to metabolic pathways and their constituent enzymes. The Katsura tool combines KEGG pathway and enzyme information with gene expression to provide insights into possible metabolic trends over time or over a set of conditions under study. More information on Katsura can be found at the Katsura Tool's homepage.