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June 9, 2008
The APEX Quantitative Proteomics Tool v1.0 Release data version 1.0.0 release
The NIAID sponsored Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute has developed a software tool that computes protein abundance values based on standard liquid chromatography tandem mass spectrometry (LC-MS/MS) proteomics datasets. The APEX Quantitative Proteomics Tool is a free open source tool that can be utilized by proteomics researchers to simultaneously quantify hundreds to thousands of proteins based on LC-MS/MS results. The APEX Tool is an implementation of the Absolute Protein Expression (APEX) quantitation technique developed by members of the Marcotte Lab at the University of Texas at Austin [Lu et al. Nature Biotech. 25(1):117-124, 2007]. The APEX Tool provides an intuitive graphical user interface, an integrated help page system, a complete manual, and a tutorial and sample data set. Additional information and APEX downloads can be found on the APEX Tool's homepage.